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Home / Proteins & Peptide

Recombinant Human DAPK1 (N-GST tag)

SKU : BHP10901162

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500099
Description	Death-associated protein kinase 1 (DAPK1) is a positive mediator of apoptosis induced by ?-interferon. Activation of DAPK occurs via dephosphorylation of Ser-308 and subsequent association of calcium/calmodulin . DAPK is rapidly dephosphorylated in response to tumor necrosis factor or ceramide and then subsequently degraded via proteasome activity. The decline in DAPK expression is paralleled with increased caspase activity and cell apoptosis. Studies suggest that the apoptosis regulatory activities mediated by DAPK are controlled both by phosphorylation status and protein stability .
Alternative Names	DAPK ; DKFZp781I035
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of DAPK1 was determined to be49 nmol /min/mg as per activity assay protocol.

Weight	71.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901162	Z500099	10µg	$361.11		Add to Cart

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