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Home / Proteins & Peptide

Recombinant Human CSNK1A1/CKI-alpha/CK1 Protein (GST Tag)(Active)

SKU : BHP10300094

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030400
Description	A DNA sequence encoding the full length of human CSNK1A1 isoform 1 (P48729-1) (Met 1-Phe 337) was expressed with the GST tag at the N-terminus.
Alternative Names	CK1 ; HLCDGP1 ; PRO2975
Background	Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are useful prognosis markers in non-small cell lung cancer (NSCLC) patients after complete resection, independent of lymph node metastasis status. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. It phosphorylates CTNNB1 at 'Ser-45'. CSNK1A1 may play a role in segregating chromosomes during mitosis.
Tag	GST tag
Regulatory	RUO
Host	Baculovirus-Insect Cells
Endotoxin Level	< 1.0 EU per μg of the protein as determined by the LAL method
Nature	Recombinant

Shipping	Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Buffer	Supplied as sterile 20mM Tris, 500mM NaCl, 2mM GSH, pH 7.4
Description	Please refer to the printed manual for detailed information.
Purity	> 90 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300094	PKSH030400	50ug	$717		Add to Cart

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