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Home / Proteins & Peptide

Recombinant Human CRADD/RAIDD Protein (His Tag)

SKU : BHP10300347

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030770
Description	A DNA sequence encoding the human CRADD (P78560) (Met 1-Glu 199) was fused with a polyhistidine tag at the C-terminus.
Alternative Names	MGC9163 ; RAIDD
Background	Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. CRADD/ RAIDD contains one CARD domain and one death domain. CRADD/ RAIDD contains a death domain involved in the binding of RIP protein. The CARD domain mediates the interaction with caspase-2. FADD/ MORT1 is a death domain (DD)-containing adaptor/ signaling molecule that interacts with the intracellular DD of FAS/ APO-I ( CD95 ) and tumor necrosis factor receptor 1 and the prodomain of caspase-8 ( Mch5/ MACH/ FLICE). CRADD/ RAIDD has a dual-domain structure similar to that of FADD. CRADD/ RAIDD has an NH2-terminal caspase homology domain that interacts with caspase-2 and a COOH-terminal DD that interacts with RIP. CRADD/ RAIDD could play a role in regulating apoptosis in mammalian cells. CRADD/ RAIDD is a apoptotic adaptor molecule specific for caspase-2 and FASL/ TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD/ RAIDD recruits caspase-2 to the TNFR-1 signalling complex.
Tag	His tag
Regulatory	RUO
Host	E. coli
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, 20% glycerol, pH 8.0
Description	Please refer to the printed manual for detailed information.
Purity	> 95 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300347	PKSH030770	100ug	$855		Add to Cart

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