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Home / Proteins & Peptide

Recombinant Human Complement C1q subcomponent subunit A(C1QA)

SKU : BHP10505582

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP003637HUb1
Antigen	C1QA
Tag	N-terminal 10xHis-tagged and C-terminal Myc-tagged
Description	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Regulatory	RUO
Relevance	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2?proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	23-245aa
Mol Weight	30.7 kDa
Nature	Recombinant
Protein Description	Full Length of Mature Protein

Involvement In Disease	Complement component C1q deficiency (C1QD)
Subcellular Location	Secreted
Uniprot	P02745, P02745
Database Links	HGNC:1241 OMIM:120550 KEGG:hsa:712 STRING:9606.ENSP00000363773 UniGene:Hs.632379
Function	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Pathway	Complement and coagulation cascades
Research Area	Immunology
Weight	30.7 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer，50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505582	CSB-EP003637HUb1	1mg	$1812		Add to Cart
BHP10505582	CSB-EP003637HUb1	100ug	$419		Add to Cart
BHP10505582	CSB-EP003637HUb1	20ug	$224		Add to Cart

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