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Home / Proteins & Peptide

Recombinant Human CLDN18.2(N-6His,C-Avi)

SKU : BHP10306246

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH034071
Reconstitution	Not Applicable
Background	Claudin-18(CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2.IMAB362 (Claudiximab) is a monoclonal antibody against isoform 2 of Claudin-18. It is underinvestigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG.
Tag	N-6His,C-Avi
Formulation	Supplied as a 0.2 um filtered solution of 20mM Tris, 8M Urea,150mM NaCl, 5mM beta-ME, pH 8.5.
Species	Human
Host	E.coli
Accession Number	P56856-2
Endotoxin Level	< 1.0 EU per g as determined by the LAL method.
Accurate Molecular Mass(kd)	12.6 kDa
Predicted Molecular Mass(kd)	13 kDa
Protein Description	Biotinylated Recombinant Human CLDN18.2 is produced by our E.coli expression system and the targetgene encoding extracellular is expressed with a 6His tag at the N-terminus.

Synonyms	Claudin-18.2; CLDN18

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Purity	> 95 % as determined by reducing SDS-PAGE.
Storage	Store at< -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Immunological Activity	Test in progress

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SKU	Supplier No.	Size	Your price	Quantity
BHP10306246	PKSH034071	20ug	$775		Add to Cart
BHP10306246	PKSH034071	100ug	-		Add to Cart

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