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Home / Proteins & Peptide

Recombinant Human CK1 alpha 1 (N-GST tag)

SKU : BHP10900243

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500083
Description	CK1a1 is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes. CK1a1 can regulate Smo cell surface accumulation and activity in response to hedgehog. CK1a1 phosphorylate Smo at several sites and phosphorylation-deficient forms of Smo fail to accumulate on the cell surface and are unable to transduce the hedgehog signal . CK1a1 dynamically associates with the CBM complex on T cell receptor engagement to participate in cytokine production and lymphocyte proliferation. CK1a1 can form complex with MDM2 which then regulates the stability of p53 and E2F-1 transcription factors .
Alternative Names	CK1 ; HLCDGP1 ; PRO2975 ; CK1A1 ; CSNK1A1
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of CK1a1 was determined to be 120 nmol /min/mg as per activity assay protocol.

Weight	62.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900243	Z500083	10µg	$361.11		Add to Cart

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