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Home / Proteins & Peptide

Recombinant Human CHK2 (N-GST tag)

SKU : BHP10900543

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500082
Description	CHK2 is rapidly phosphorylated and activated in response to replication blocks and DNA damage; the response to DNA damage occurs in an ataxia telangiectasia mutated (ATM)-dependent manner . Expression of wild-type Chk2 leads to increased p53 stabilization after DNA damage, whereas expression of a dominant-negative Chk2 mutant abrogated both phosphorylation of p53 on Ser-20 and p53 stabilization .
Alternative Names	CHEK2 ; HuCds1 ; LFS2 ; PP1425 ; RAD53 ; RP11-436C9.1 ; CDS1
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of CHK2 was determined to be 808 nmol /min/mg as per activity assay protocol.

Weight	88.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900543	Z500082	10µg	$361.11		Add to Cart

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