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Home / Proteins & Peptide

Recombinant Human CDCP1/CD318 Protein (aa 30-341, His Tag)

SKU : BHP10304272

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033302
Description	Recombinant Human CUB domain-containing protein 1 is produced by our Mammalian expression system and the target gene encoding Phe30-Ser341 is expressed with a 6His tag at the C-terminus.
Alternative Names	CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD318;TRASK
Reconstitution	Please refer to the printed manual for detailed information.
Background	CUB domain-containing protein 1(CDCP1) is a transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains; and a smaller intracellular domain (ICD) containing five tyrosines. CDCP1 is widely expressed in human epithelial tissues; but its phosphorylation is only seen in mitotically detached or shedding cells; consistent with its role in the negative regulation of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsinor EDTA; or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype.
Reactivity	Human
Tag	C-6His
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM PB;150mM NaCl;pH7.4.
Host	Human Cells
Accession Number	Q9H5V8-3
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	36.1 kDa
Mw(kda)	36.1 kDa

Sequence Info	Phe30-Ser341

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304272	PKSH033302	10ug	$129		Add to Cart
BHP10304272	PKSH033302	50ug	$375		Add to Cart

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