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Home / Proteins & Peptide

Recombinant Human CD5 Protein (His Tag)(Active)

SKU : BHP10302925

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031299
Description	A DNA sequence encoding the human CD5 (NP_055022.2) extracellular domain (Met 1-Pro 372) was expressed with a polyhistidine tag at the C-terminus.
Alternative Names	LEU1;T1
Reconstitution	Please refer to the printed manual for detailed information.
Background	The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.
Reactivity	Human
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_055022.2
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	Measured by its ability to bind biotinylated recombinant human LCK in a functional ELISA.
Mol Weight	40 kDa
Mw(kda)	40 kDa

Sequence Info	Met 1-Pro 372

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302925	PKSH031299	100ug	$732		Add to Cart

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