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Home / Proteins & Peptide

Recombinant Human CD40L/TNFSF5 Protein (E.coli)(Active)

SKU : BHP10304678

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033725
Description	Recombinant Human CD40L is produced by our E.coli expression system and the target gene encoding Met113-Leu261 is expressed.
Alternative Names	CD40 Ligand; CD40-L; T-Cell Antigen Gp39; TNF-Related Activation Protein; TRAP; Tumor Necrosis Factor Ligand Superfamily Member 5; CD154; CD40LG; CD40L; TNFSF5; TRAP;hCD40L;HIGM1;IGM;IMD3;T-BAM;TNFSF5;TRAP
Reconstitution	Please refer to the printed manual for detailed information.
Background	CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members; CD40LG exists as a trimer in membrane bound and soluble form; both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma; TNF-alpha; and IL2.
Reactivity	Human
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM PB; 200mM NaCl; 0.1mM EDTA; pH 7.0.
Host	E.coli
Accession Number	P29965
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Bioactivity	Immobilized Human CD40L at 5ug/ml(100 ul/well) can bind Human CD40-Fc(Cat: PKSH032216). The ED50 of Human CD40L is 68.55ug/ml.
Mol Weight	16.2 kDa
Mw(kda)	16.2 kDa

Sequence Info	Met113-Leu261

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304678	PKSH033725	10ug	$62		Add to Cart
BHP10304678	PKSH033725	50ug	-		Add to Cart

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