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Home / Proteins & Peptide

Recombinant Human CD40 Ligand (CD40LG)

SKU : BHP10900704

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z100127
Description	CD40LG protein is expressed on all B lymphocytes during various stages of development, activated T cells and monocytes, follicular dendritic cells, thymic epithelial cells, and various carcinoma cell lines. It is expressed on most mature B cell malignancies and on some early B cell acute lymphocytic leukemias. Human CD40LG has been found to be the receptor for a protein involved in an X-linked immunodeficiency syndrome. Based on its homology with other members of the TNF ligand protein superfamily, CD40LG is also referred to also as TNFSF5. The soluble form of CD40LG is generated by the intracellular proteolytic processing of the full length CD40LG. Recombinant Human CD40LG is a 17 kDa protein that represents the soluble segment of full length CD40LG and encompasses the receptor binding TNF-like domain.
Alternative Names	CD154 ; gp39 ; T-BAM ; CD40 ; T cell antigen Gp39 ; CD-40L ; Soluble CD40 Ligand ; Tumor necrosis factor ligand superfamily member 5 ; TNFSF5 ; TNF-related activation protein ; TRAP
Quantity	250 µg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED50 as determined by dose-dependent proliferation of acute myeloid leukemia was found to be <5 ng/ml

Weight	16.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.0)
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900704	Z100127	250µg	$269.44		Add to Cart

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