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Home / Proteins & Peptide

Recombinant Human Cathepsin S/CTSS Protein (His Tag)(Active)

SKU : BHP10304689

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033736
Description	Recombinant Human Cathepsin S is produced by our Mammalian expression system and the target geneencoding Gln17-Ile331(pro)&Ser109-Ile331&Gln17-Ser109(Propeptide) is expressed with a 6His tag atthe C-terminus.
Alternative Names	Cathepsin S;CTSS;CTSS;MGC3886
Reconstitution	Please refer to the printed manual for detailed information.
Background	Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, LandH, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimers disease(AD) and Down Syndrome (DS).
Reactivity	Human
Tag	C-His
Formulation	Supplied as a 0.2 um filtered solution of 20mM MES, 150mM NaCl, 10% Glycerol, pH 5.5.
Host	Human Cells
Accession Number	P25774
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Bioactivity	Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 The specific activity is 9063.642 pmol/min/µg.
Mol Weight	36.9&25&11.2 kDa
Mw(kda)	36.9&25&11.2 kDa

Sequence Info	Gln17-Ile331(pro)&Ser109-Ile331&Gln17-Ser109(Propeptide)

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 90% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304689	PKSH033736	10ug	$263		Add to Cart
BHP10304689	PKSH033736	50ug	$447		Add to Cart

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