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Home / Proteins & Peptide

Recombinant Human Carbonyl reductase family member 4(CBR4)

SKU : BHP10503819

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP850803HU
Alternative Names	3-ketoacyl-[acyl-carrier-protein] reductase beta subunit
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones
Source	E.coli
Abbreviation	CBR4
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Carbonyl reductase family member 4; EC= 1.-.-.-; Alternative name(s): 3-oxoacyl-[acyl-carrier-protein] reductase; EC= 1.1.1.-; Quinone reductase CBR4
Expression Region	1-237aa
Mol Weight	52.3kDa
Nature	recombinant
Protein Description	Full Length

Subcellular Location	Mitochondrion matrix
Uniprot	Q8N4T8, Q8N4T8
Database Links	HGNC:25891 KEGG:hsa:84869 STRING:9606.ENSP00000303525 UniGene:Hs.659311
Function	The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis
Protein Families	Short-chain dehydrogenases/reductases (SDR) family
Research Area	Signal Transduction
Tissue Specificity	Detected in liver and kidney (at protein level).
Weight	53.707kD

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503819	CSB-EP850803HU	1mg	$1812		Add to Cart
BHP10503819	CSB-EP850803HU	100ug	$419		Add to Cart
BHP10503819	CSB-EP850803HU	20ug	$224		Add to Cart

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