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Home / Proteins & Peptide

Recombinant Human C-type lectin domain family 4 member C(CLEC4C),parial (Active)

SKU : BHP10506659

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP855470HU
Alternative Names	Blood dendritic cell antigen 2 ,BDCA-2,C-type lectin superfamily member 7Dendritic lectin, CD303
Antigen	CLEC4C
Relevance	Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not se to bind mannose.
Source	E.coli
Abbreviation	CLEC4C
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: C-type lectin domain family 4 member C; Alternative name(s): Blood dendritic cell antigen 2; Short name= BDCA-2; C-type lectin superfamily member 7; Dendritic lectin; CD_antigen= CD303
Expression Region	45-213aa
Mol Weight	36.0kDa
Protein Description	Partial

Subcellular Location	Cell membrane, Single-pass type II membrane protein
Uniprot	Q8WTT0
Database Links	HGNC:13258 OMIM:606677 KEGG:hsa:170482 STRING:9606.ENSP00000353500 UniGene:Hs.351812
Function	Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells
Research Area	Immunology
Tissue Specificity	Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.

Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer，50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10506659	CSB-EP855470HU	1mg	$1812		Add to Cart
BHP10506659	CSB-EP855470HU	100ug	$419		Add to Cart
BHP10506659	CSB-EP855470HU	20ug	$224		Add to Cart

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