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Home / Proteins & Peptide

Recombinant Human C-C motif chemokine 16(CCL16)

SKU : BHP10500392

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP004779HU
Alternative Names	Chemokine CC-4 ,HCC-4,Chemokine LEC,IL-10-inducible chemokine,LCC-1,Liver-expressed chemokineLymphocyte and monocyte chemoattractant ,LMCMonotactin-1 ,MTN-1NCC-4,Small-inducible cytokine A16, Chemokine CC-4 ; HCC-4 ; Chemokine LEC ; IL-10-inducible chemokine ; LCC-1 ; Liver-expressed chemokineLymphocyte and monocyte chemoattractant ; LMCMonotactin-1 ; MTN-1NCC-4 ; Small-inducible cytokine A16
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Shows chotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	24-120aa
Mol Weight	27.2kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	O15467, O15467
Database Links	HGNC:10614 OMIM:601394 KEGG:hsa:6360 STRING:9606.ENSP00000293275 UniGene:Hs.10458
Function	Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
Pathway	Chemokine signaling pathway
Protein Families	Intercrine beta (chemokine CC) family
Research Area	Immunology
Tissue Specificity	Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
Weight	27.2kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500392	CSB-EP004779HU	1mg	$1812		Add to Cart
BHP10500392	CSB-EP004779HU	100ug	$419		Add to Cart
BHP10500392	CSB-EP004779HU	20ug	$224		Add to Cart

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