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Home / Proteins & Peptide

Recombinant Human BUB1B (N-GST tag)

SKU : BHP10900331

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500045
Description	BUB1B or budding uninhibited by benzimidazoles 1 homolog beta is involved in spindle checkpoint function and has been localized to the kinetochore. BUB1B plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation . BUB1B links the regulation of chromosome-spindle attachment to mitotic checkpoint signaling . BUB1B expression during the spindle checkpoint is dependent on residual BUB1B expression and impaired spindle checkpoint function has been found in many forms of cancer. BUB1B is essential for early embryonic development and normal hematopoiesis.
Alternative Names	hBUBR1 ; BUB1beta ; SSK1 ; BUBR1 ; Bub1A ; MAD3L
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of BUB1B was determined to be 1.5 nmol /min/mg as per activity assay protocol

Weight	73.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900331	Z500045	10µg	$361.11		Add to Cart

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