BMP-7(osteogenic protein- 1) is produced in the kidney and in the nervous system. It is produced also by human fetal trophoblasts in vivo and may be involved in the regulation of the synthesis of chorionic gonadotropin and progesterone by trophoblasts. BMP7 induces new bone growth, and forms heterodimers with BMP2A. The factor is a member of the TGF family of proteins.
Alternative Names
Osteogenic protein 1 ; OP-1 ; INN=Eptotermin alfa ; BMP7
Quantity
10 µg
Regulatory
RUO
Source
E. coli
Host
Human
Endotoxin Level
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment
Not available.
Weight
17.0 kDa
Description
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format
Lyophilized PowderRecombinant BMP-7 was lyophilized from a 0.2 μm filtered PBS solution pH 7.4.
Purity
>95% as determined by SDS-PAGE
Storage
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.