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Recombinant Human Beta-nerve growth factor(NGF),partial (Active)

BHP10506492
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Email
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Involvement In Disease Neuropathy, hereditary sensory and autonomic, 5 (HSAN5)
Subcellular Location Secreted
Uniprot P01138
Database Links

HGNC:7808

OMIM:162030

KEGG:hsa:4803

STRING:9606.ENSP00000358525

UniGene:Hs.2561
Function Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI
Pathway MAPK signaling pathway; PI3K-Akt signaling pathway; Apoptosis; Ras signaling pathway; Rap1 signaling pathway; Inflammatory Pain; Inhibitors of axonal regeneration
Protein Families NGF-beta family
Research Area Neuroscience
Purity Greater than 95% as determined by SDS-PAGE.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 250 mM NaCl, pH 7.0
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506492 CSB-AP003951HU 1mg $1836
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BHP10506492 CSB-AP003951HU 500ug $1160
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BHP10506492 CSB-AP003951HU 50ug $174
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