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Home / Proteins & Peptide

Recombinant Human B-cell lymphoma/leukemia 10(BCL10)

SKU : BHP10500354

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP002608HU
Alternative Names	B-cell CLL/lymphoma 10 ,hCLAPCED-3/ICH-1 prodomain homologous E10-like regulator ,CIPER,Cellular homolog of vCARMEN ,cCARMENCellular-E10 ,c-E10Mammalian CARD-containing adapter molecule E10 ,mE10, B-cell CLL/lymphoma 10 ; hCLAPCED-3/ICH-1 prodomain homologous E10-like regulator ; CIPER ; Cellular homolog of vCARMEN ; cCARMENCellular-E10 ; c-E10Mammalian CARD-containing adapter molecule E10 ; mE10
Antigen	BCL10
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Involved in adaptive immune response . Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 .
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-233aa
Mol Weight	42.3kDa
Nature	recombinant
Protein Description	Full Length

Involvement In Disease	Immunodeficiency 37 (IMD37); Lymphoma, mucosa-associated lymphoid type (MALTOMA)
Subcellular Location	Cytoplasm, perinuclear region, Membrane raft
Uniprot	O95999, O95999
Database Links	HGNC:989 OMIM:137245 KEGG:hsa:8915 STRING:9606.ENSP00000271015 UniGene:Hs.193516
Function	Involved in adaptive immune response
Pathway	NF-kappa B signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway
Research Area	Apoptosis
Tissue Specificity	Ubiquitous.
Weight	42.2kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500354	CSB-EP002608HU	1mg	$1812		Add to Cart
BHP10500354	CSB-EP002608HU	100ug	$419		Add to Cart
BHP10500354	CSB-EP002608HU	20ug	$224		Add to Cart

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