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Home / Proteins & Peptide

Recombinant Human B-cell Activating Factor (TNFSF13B)

SKU : BHP10901248

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z100967
Description	The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.
Alternative Names	B cell Activating Factor belonging to the TNF family ; BAFF ; Tumor necrosis factor ligand superfamily member 13B ; TNFSF13B ; TNFSF20 ; B lymphocyte stimulator ; BLys ; THANK ; Dendritic cell-derived TNF-like molecule ; TNF- and APOL-related leukocyte expressed ligand 1 ; TALL-1 ; CD_antigen=CD257
Appearance	Lyophilized Powder
Reconstitution	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Formulation	Recombinant Human BAFF was lyophilized from a 0.2 μm filtered solution in PBS, pH 7.5.
Molecular Weight	18.0 kDa
Quantity	100 µg
Source	E. coli
Usage	For research use only. Not for diagnostic or therapeutic use.
Accession Number	Q9Y275
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Bioactivity	The ED(50) was determined by a cell proliferation assay using anti-IgM stimulated murine B cells, and is less than 2.0 ng/mL, corresponding to a specific activity of 5.0 x 10^5 IU/mg

Gene Id	10673
Gene Name	TNFSF13B

Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor eFlyer

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901248	Z100967	100µg	$219.44		Add to Cart

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