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Home / Proteins & Peptide

Recombinant Human AURORA C (N-GST tag)

SKU : BHP10901206

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500035
Description	Aurora C is a member of mitotic serine/threonine kinases that regulate centrosome maturation, chromosome segregation, and cytokinesis. Aurora C has been shown to contribute to oncogenic transformation and is frequently overexpressed and amplified in many human tumors . Aurora C overexpression has been correlated with centrosome amplification, which can be a driving cause of genomic instability in tumor cells. Aurora C is an important regulator of both genomic integrity and cell cycle progression in cancer cells and is an attractive target for anticancer drug development .
Alternative Names	STK13 ; aurora-C ; AURKC ; AIE2 ; AIK3 ; AurC
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of AURORA C was determined to be 65 nmol /min/mg as per activity assay protocol

Weight	61.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901206	Z500035	10µg	$361.11		Add to Cart

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