Recombinant Human Aspartyl/asparaginyl beta-hydroxylase(ASPH),partial

Mfr.No.	CSB-EP002226HU
Alternative Names	Aspartate beta-hydroxylase ,ASP beta-hydroxylase,Peptide-aspartate beta-dioxygenase, Aspartate beta-hydroxylase ; ASP beta-hydroxylase ; Peptide-aspartate beta-dioxygenase
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	75-270aa
Mol Weight	38.2kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	Facial dysmorphism, lens dislocation, anterior segment abnormalities, and spontaneous filtering blebs (FDLAB)
Subcellular Location	Isoform 1: Endoplasmic reticulum membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Isoform 4: Sarcoplasmic reticulum membrane, Single-pass type II membrane protein, SUBCELLULAR LOCATION: Isoform 8: Endoplasmic reticulum membrane, Single-pass type II membrane protein
Uniprot	Q12797, Q12797
Database Links	HGNC:757 OMIM:600582 KEGG:hsa:444 STRING:9606.ENSP00000368767 UniGene:Hs.332422
Function	Isoform 1
Protein Families	Aspartyl/asparaginyl beta-hydroxylase family
Research Area	Signal Transduction
Tissue Specificity	Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart, brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level).
Weight	38.2kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol