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Home / Proteins & Peptide

Recombinant Human Arachidonate 5-lipoxygenase-activating protein(ALOX5AP)

SKU : BHP10505942

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-CF001625HU
Description	Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Alternative Names	FLAP MK-886-binding protein
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Source	in vitro E.coli expression system
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	FLAP; MK-886-binding protein
Expression Region	1-161aa
Mol Weight	34.2 kDa
Nature	Recombinant
Protein Description	Full Length

Involvement In Disease	Ischemic stroke (ISCHSTR)
Subcellular Location	Nucleus membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane, Multi-pass membrane protein
Uniprot	P20292, P20292
Database Links	HGNC:436 OMIM:601367 KEGG:hsa:241 STRING:9606.ENSP00000369858 UniGene:Hs.507658
Function	Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Pathway	Fc epsilon RI signaling pathway
Protein Families	MAPEG family
Research Area	Cardiovascular
Weight	34.2 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer，50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505942	CSB-CF001625HU	100ug	$3165		Add to Cart
BHP10505942	CSB-CF001625HU	20ug	$1823		Add to Cart

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