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Home / Proteins & Peptide

Recombinant Human ALK4 (N-GST tag)

SKU : BHP10900169

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500012
Description	ALK4 is a member of the subfamily of receptor ser/thr kinases that mediates signaling by the Activins. ALK4 is expressed in many human tissues, including kidney, pancreas, brain, lung, and liver. Truncated ALK4, predominantly expressed in human pituitary adenomas, function as dominant negative receptors to interfere with wild-type receptor function and blocks the antiproliferative effect of activin possibly contributing to development of human pituitary tumors . ALK4 is able to mediate Nodal signaling in the presence of Cripto during vertebrate development .
Alternative Names	ACVR1B ; SKR2 ; ACTRIB ; ACVRLK4
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of ALK4 was determined to be 16 nmol /min/mg as per activity assay protocol.

Weight	64.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900169	Z500012	10µg	$361.11		Add to Cart

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