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Home / Proteins & Peptide

Recombinant Human AKR1B1 Protein (His Tag)

SKU : BHP10302894

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031165
Description	A DNA sequence encoding the human AKR1B1 (P15121) (Met 1-Phe 316) was expressed, with a polyhistidine tag at the N-terminus.
Alternative Names	ADR;ALDR1;ALR2;AR;MGC1804
Reconstitution	Please refer to the printed manual for detailed information.
Background	Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the collecting tubule cells and thought to provide protection against hypertonic environment. Some human tissues contain AKR1B1 as well as AKR1B10, a closely related member of the aldo-keto reductase superfamily.
Reactivity	Human
Tag	N-His
Formulation	Lyophilized from sterile PBS, 20% glycerol, pH 7.5
Host	E.coli
Accession Number	P15121
Endotoxin Level	Please contact us for more information.
Mol Weight	37.9 kDa
Mw(kda)	37.9 kDa

Sequence Info	Met 1-Phe 316

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302894	PKSH031165	100ug	$609		Add to Cart

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