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Home / Proteins & Peptide

Recombinant Human Acyl-CoA 6-desaturase(FADS2),partial

SKU : BHP10503131

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP007960HU
Alternative Names	Acyl-CoA 6-desaturase, Delta(6) fatty acid desaturase, D6D, Delta(6) desaturase, Delta-6 desaturase, Acyl-CoA 6-desaturase ; Delta(6) fatty acid desaturase ; D6D ; Delta(6) desaturase ; Delta-6 desaturase
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-131aa
Mol Weight	30.9kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Endoplasmic reticulum membrane, Multi-pass membrane protein
Uniprot	O95864, O95864
Database Links	HGNC:3575 OMIM:606149 KEGG:hsa:9415 STRING:9606.ENSP00000278840 UniGene:Hs.502745
Function	Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18
Pathway	PPAR signaling pathway
Protein Families	Fatty acid desaturase type 1 family
Research Area	Cardiovascular
Tissue Specificity	Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with poor prognostic inde
Weight	30.89kD

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503131	CSB-EP007960HU	1mg	$2466		Add to Cart
BHP10503131	CSB-EP007960HU	100ug	$578		Add to Cart
BHP10503131	CSB-EP007960HU	20ug	$306		Add to Cart

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