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Home / Proteins & Peptide

Recombinant Human Activin A (INHBA)

SKU : BHP10901108

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z103117
Description	Part of the TGF-β family, inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic, pituitary and gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development and bone growth depending on their subunit composition. Activin A is a disulfide linked homodimer (two beta-A chains) that binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant Human Activin A is a homodimeric, non-glycosylated protein with a molecular weight of 25 kDa.
Alternative Names	Inhibin beta-A chain ; Erythroid differentiation protein ; INHBA ; FSH releasing protein ; Activin beta-A chain
Quantity	100 µg
Regulatory	RUO
Source	HEK293
Host	Human
Endotoxin Level	<1 EU/µg of recombinant protein as determined by the LAL method
Biological Activity Comment	The EC(50) as determined by the ability of proliferation inhibition of the MPC-11 cell line (mouse plasmocytoma cell line) was found to be ≤ 5 ng/mL.

Weight	25 kDa, homodimer, nonglycosylated

Description	A quick spin of the vial followed by reconstitution in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Format	Lyophilized Powder 1x PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901108	Z103117	100µg	$3972.50		Add to Cart

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