Recombinant Human ACE-2 (C-mFc)

Mfr.No.	EPT272
Description	Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a mFc tag at the C-terminus.
Alternative Names	Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
Background	Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Biological Activity	Immobilized 2019-nCoV S1 Protein (Cat#DRA35)at 10ug/ml (100ul/well) can bind Human ACE-2-mFc(Cat#C06A). The ED50 of Human ACE-2-mFc(Cat#C06A) is 45.11 ng/ml.
Molecular Weight	110 KDa
Accession Number	Q9BYF1
Endotoxin Level	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Shipping	The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Purity	Greater than 95%
Storage	Store at <=-70°C, stable for 6 months after receipt. Store at <=-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP15200272	EPT272	50ug	$729		Add to Cart