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Home / Proteins & Peptide

Recombinant Human 26S proteasome non-ATPase regulatory subunit 11 protein(PSMD11)

SKU : BHP10501658

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RP005754h
Alternative Names	26S proteasome regulatory subunit RPN626S proteasome regulatory subunit S926S proteasome regulatory subunit p44.5
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assbly. Plays a key role in increased proteasome activity in bryonic st cells (ESCs): its high expression in ESCs promotes enhanced assbly of the 26S proteasome, followed by higher proteasome activity.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	2-422aa
Mol Weight	74.3kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Nucleus, Cytoplasm, cytosol
Uniprot	O00231, O00231
Database Links	HGNC:9556 OMIM:604449 KEGG:hsa:5717 STRING:9606.ENSP00000261712 UniGene:Hs.443379
Function	Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs)
Protein Families	Proteasome subunit S9 family
Research Area	Cell Biology
Tissue Specificity	Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.
Weight	74.7kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501658	CSB-RP005754h	1mg	$1812		Add to Cart
BHP10501658	CSB-RP005754h	100ug	$419		Add to Cart
BHP10501658	CSB-RP005754h	20ug	$224		Add to Cart

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