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Home / Proteins & Peptide

Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir(tir),partial

SKU : BHP10503037

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP514896EOF
Alternative Names	Secreted effector protein Tir
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The Extracellular domain region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	252-362aa
Mol Weight	27.8kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Secreted, Host cell membrane, Multi-pass membrane protein
Uniprot	C6UYL8, C6UYL8
Database Links	KEGG:etw:ECSP_4676
Function	Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).
Protein Families	Tir receptor family
Research Area	Others
Weight	27.8kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Escherichia coli (E. coli)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503037	CSB-EP514896EOF	1mg	$2466		Add to Cart
BHP10503037	CSB-EP514896EOF	100ug	$729		Add to Cart
BHP10503037	CSB-EP514896EOF	20ug	$388		Add to Cart

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