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Home / Proteins & Peptide

PTPsigma (PTPRS), GST-tag

SKU : BHP18200040

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Mfr.No.	30045
Description	Human PTPRS (GenBank Accession No. BC104812), a.a. 883-end, with N-terminal GST-tag, MW= 98 kDa, expressed in an E. coli expression system. Specific activity: 347 pmol/min/ug
Background	PTPRS is a member of a subfamily of receptor type PTPases that is characterized by the presence of an extracellular cell adhesion molecule-like motif and 2 intracellular phosphatase domains. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis.
Immunogen Region	883-end
Tag	N-terminal GST-tag
Formulation	25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	20 mM HEPES, pH 7.2, 2 mM EDTA, 1 mM DTT, 25 mM pNPP. Assay was done at room temperature for 16 minutes, and monitored continuously at Abs405 nM. epsilon_pNPP = 18,000 M^-1cm^-1. Avoid freeze/thaw cycles.
GenBank	BC104812
Mw(kda)	98 kDa

Synonyms	PTPsigma, PTPRS, protein tyrosine phosphatase sigma, PTPsigma
Uniprot	Q13332

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	>12 months at -80°C

Reference	1. Forrest, A.R. et al., Genome Biol. 2006;7(1):R5. 2. Muise, A. and Rotin, D. Expert Rev Mol. Diagn. 2008 Jul;8(4):465-77.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200040	30045	50 ug was 20 ug	$357.50		Add to Cart

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