Pseudophosphatase PTP-IA2, also known as PTPRN and ICA-512, GenBank accession no. NM_002846, a.a. 693- 979, with an N-terminal GST-tag, MW=58.8 kDa, expressed in an E. coli expression system.
Background
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
Immunogen Region
693-979
Tag
N-terminal GST-tag
Formulation
25 mM Tris-HCl, pH 8.0, 75 mM NaCl, 0.05% Tween-20, 50% glycerol, 2 mM EDTA, 1 mM DTT, and 10 mM glutathione.
Species
Human
Application
Suitable for use as an immunogen, in binding assays or as an antigen in autoimmune assays.