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Home / Proteins & Peptide

PTH (1-84aa), Human

SKU : BHP18500009

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Mfr.No.	IX02021, IX02021-1, IX02021-10
Description	Parathyroid Hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. Parathyroid Hormone (PTH) is secreted from cells of the parathyroid glands and finds Parathyroid Hormone's major target cells in bone and kidney. Like most other protein hormones, Parathyroid Hormone (PTH) is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid Hormone (PTH) is secreted as a linear protein of 84 amino acids. Recombinant Human Parathyroid Hormone (PTH) produced in E. coli is a single, non-glycosylated, polypeptide chain containing 84 amino acids and having a molecular mass of 9,000 Da.
Reconstitution	It is recommended to reconstitute the lyophilized PTH in sterile 18 Momega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Formulation	The protein (1 mg/ml) was lyophilized after extensive dialyses against 1.15 mg sodium citrate, sodium chloride 7.31 mg, 0.21 mg citric acid, 0.1117 mg EDTA-Na2, 0.2 mg Tween 80 and 50 mg Mannitol.
Molecular Weight	9,000 Da
Source	E. coli
Host	Human
Endotoxin Level	Less than 0.1 ng/ug (1 EU/ug) of Parathyroid Hormone (PTH) .
Bioactivity	PTH is fully biologically active when compared to standards. The activity calculated by UMR106 cell/cAMP method corresponding to a specific activity of 1.0x104 U/mg.

Synonyms	PTH;

Purity	Greater than 98.0% as determined by:1. Analysis by RP-HPLC2. Anion-exchange FPLC3. Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel
Storage	Lyophilized Human Parathyroid Hormone (PTH ) remains stable at room temperature for three weeks, but it is best stored desiccated below -18°C. Upon reconstitution Human Parathyroid Hormone (PTH )should be stored at 4°C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500009-1	IX02021-1	1mg	$905		Add to Cart
BHP18500009-2	IX02021-10	10ug	$49		Add to Cart

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