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Home / Proteins & Peptide

PRMT7, FLAG-tag

SKU : BHP18200430

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Mfr.No.	51054
Description	Human PRMT7 (protein arginine methyltransferase 7), GenBank Accession No. NM_019023, a.a. 2-692(end) with N-terminal FLAG-tag, MW=80 kDa, expressed in Sf9 cells using a Baculovirus expression system. host species: insect Host species: insect Host cell line: Sf9
Background	Three types of arginine methylation exist in mammalian cells: monomethylarginine (MMA), asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA). Type I PRMTs ((CARM1, PRMT1, PRMT2, PRMT3, PRMT6, and PRMT8) catalyze ADMA, while type II PRMTs (e.g. PRMTs 5 and 7) catalyze SDMA. Type II PRMTs are found to be strongly implicated in diseases like cancer. For example, PRMT5 plays a role in the repression of certain tumor suppressor genes such as RB tumor suppressors while PRMT7 overexpression is observed in breast cancer
Immunogen Region	2-692(end)
Tag	N-terminal FLAG-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ug/ml FLAG peptide, 3 mM DTT, 20% glycerol
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_019023
Mw(kda)	80 kDa

Synonyms	protein arginine N-methyltransferase 7, PRMT7, Histone-arginine N-methyltransferase7
Uniprot	Q9NVM4

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Miranda, T.B., et al. J. Biol. Chem. 2004 May 28,279(22):22902-7 2. Lee, J.H., et al. J. Biol. Chem. 2005 Feb 4,280(5):3656-64.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200430	51054	20 ug	$495		Add to Cart

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