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Home / Proteins & Peptide

PRL2 (2-167), His-tag

SKU : BHP18200024

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BPS Bioscience

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Mfr.No.	30001
Description	Human PRL 2 (GenBank Accession No. NM_080391), a.a. 2-167 with N-terminal His-tag, MW = 19.1 kDa, expressed in an E. coli expression system. Specific activity: 0.334 pmol/min/ug
Background	Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
Immunogen Region	2-167
Tag	N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2mM KCl, 20% glycerol, and 3 mM DTT.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Assay conditions: enzyme was incubated in 50 mM Tris pH 7.4, 150 mM NaCl, 5 mM DTT, and 12.5 mM PNPP as a substrate for 2 hours at 37°C. Absorbance was read by Tecan spectraphotometer at 405 nm wavelength. Avoid freeze/thaw cycles.
GenBank	NM_080391
Mw(kda)	19.1 kDa

Synonyms	PRL-2, PTP4A2, PTPIVa, PTPCAAX2, OV-1, Phosphatase Of Regenerating Liver 2
Uniprot	Q12974

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	>12 months at -80°C

Reference	1. Dumaual C.M. et al., J. Histochem. Cytochem. 54 (12), 1401-1412 (2006). 2. Radke I. et al., Br. J. Cancer 95 (3), 347-354 (2006).

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200024	30001	50 ug	$357.50		Add to Cart

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