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Home / Proteins & Peptide

PRL1 (2-173), His-tag

SKU : BHP18200023

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BPS Bioscience

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Mfr.No.	30000
Description	Human PRL 1 (GenBank Accession No. BC023975), a.a. 2-173 with N-terminal His-tag, MW = 19.8 kDa, expressed in an E. coli expression system. Specific activity: 0.168 pmol/min/ug
Background	Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.
Immunogen Region	2-173
Tag	N-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Assay conditions: enzyme was incubated in 50 mM Tris pH 7.4, 150 mM NaCl, 5 mM DTT, and 12.5 mM PNPP as a substrate for 2 hours at 37°C. Absorbance was read by Tecan spectraphotometer at 405 nm wavelength. Avoid freeze/thaw cycles.
GenBank	BC023975
Mw(kda)	19.8 kDa

Synonyms	PRL-1, PTP4A1, PTPIVa, PTPCAAX1, Phosphatase Of Regenerating Liver 1
Uniprot	Q93096

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	>12 months at -80°C

Reference	1. Luo Y. et al., Biochemistry. 2009. 48(8): 1838-1846 2. Sun J.P. et al., J Biol Chem. 2007 Sep 28,282(39):29043-51.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200023	30000	50 ug	$357.50		Add to Cart

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