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Home / Proteins & Peptide

PLK3 Polo Box Domain, MBP-tag, His-tag

SKU : BHP18200390

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BPS Bioscience

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Mfr.No.	50302
Description	Human N-terminal MBP tagged Plk3 polo box domain (GenBank Accession No.NM_004073/NP_004064), a.a. 335-646 with C-terminal His-tag, MW=80.5 kDa, expressed in an E. coli expression system.
Background	PLK3 or Polo-like kinase 3 is a cytokine-inducible kinase that is a member of the Polo family of serine/threonine protein kinases. PLK3 contains both a catalytic domain and a putative regulatory domain and plays an important role in the regulation of cell cycle progression and tumorigenesis. PLK3 is closely associated with centrosomes in several human cell lines and its localization is dependent on the integrity of microtubules. Hence, PLK3 is also involved in regulating microtubule dynamics and centrosomal function.
Immunogen Region	335-646
Tag	N-terminal MBP-tag, C-terminal His-tag
Formulation	45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 10% glycerol, 225 mM imidazole, and 3 mM DTT.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_004073
Mw(kda)	80.5 kDa

Synonyms	CNK, FNK, PRK, polo-like kinase 3
Uniprot	Q9H4B4

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Li, Z., et al., J. Biol. Chem. 280 (17), 16843-16850 (2005). 2.Xie,S., et al., Oncogene 23 (21), 3822-3829 (2004).

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200390	50302	100 ug	$456.50		Add to Cart

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