Human Programmed Cell Death 1 Ligand 1 (PD-L1), also known as CD274 and B7 homolog 1 (B7-H1), PDCD1 ligand 1, programmed death ligand 1, PDCD1L1, GenBank Accession No. NM_014143, a.a. 19-239, with a C-terminal FLAG-tag, expressed in a HEK293 cell expression system. MW = 26 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
19-239
Tag
C-terminal FLAG-tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Human
Application
Useful for studying protein binding and for screening small molecules and antibodies.
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_014143
Mw(kda)
26 kDa
Synonyms
Programmed Cell Death 1 Ligand 1,CD274 and B7 homolog 1 (B7-H1), PDCD1 ligand 1, programmed death ligand 1, PDCD1L1
Uniprot
Q9NZQ7
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Freeman, G.J., et al. J. Exp. Med. 2000; 192(7): 1027-1034 2. Dong, H., et al., Nat. Med. 1999; 5(12): 1365-1369.