Human secreted programmedcell death 1 (PD-1), also known as PDCD1,SLEB2, CD279 and HPD-L, GenBankAccession No. NM_005018, a.a. 25-167,with C-terminal FLAG-Avi-His-tags, MW=20kDa, expressed in a HEK293 cellexpression system. The protein isenzymatically biotinylated using AviTagtechnology. This protein runs at a higherM.W. by SDS-PAGE due to glycosylation.
Immunogen Region
25-167
Tag
C-terminal FLAG-Avi-His-tags
Formulation
8 mM Phosphate, pH 7.4,110 mM NaCl, 2.2 mM KCl, and 20%glycerol
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Notes
Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_005018
Mw(kda)
20 kDa
Synonyms
Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L
Uniprot
Q15116
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Shinohara, T., et al., Genomics. 1994Oct;23(3):704-6. 2. James, E.S., et al., Genes Immun. 2005Aug;6(5):430-7.