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Home / Proteins & Peptide

PCGF6, GST-tag

SKU : BHP18200487

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Mfr.No.	55016
Description	Human Polycomb group RING finger protein 6 (PCGF6), GenBank Accession No. NM_001011663, a.a. 2-350 (end), with N-terminal GST-tag, MW=65.7 kDa, expressed in a baculovirus expression system. host species: Sf9 cells Host species: Sf9 cells
Background	Transcriptional repressor that modulates the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.
Immunogen Region	2-350 (end)
Tag	N-terminal GST-tag
Formulation	40 mM Tris. pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.
Species	human
Application	Useful for protein binding assays, screening inhibitors, and selectivity profiling.
Notes	Avoid freeze/thaw cycles.
GenBank	NM_001011663.1
Mw(kda)	65.7 kDa

Synonyms	Polycomb group RING finger protein 6, PCGF6, Mel18 And Bmi1-Like RING Finger Protein, MBLR, RNF134
Uniprot	Q9BYE7

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Junco SE, et al.,Structure. 2013; 21(4):665-71. 2. Kajiume T, et al., Exp Hematol. 2012; 40(9):751-760.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200487	55016	50 ug	$500.50		Add to Cart

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