Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, (GenBank Accession No. NM_018313), a.a. 782-872 corresponding to bromodomain 6 with N-terminal His-tag, MW = 12 kDa, expressed in an E. coli expression system.
Immunogen Region
782-872
Tag
N-terminal His-tag
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 400 mM imidazole and 20% glycerol.
Species
Human
Application
Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Notes
Avoid freeze/thaw cycles.
GenBank
NM_018313
Mw(kda)
12 kDa
Synonyms
PBRM1, BRG1-associated factor 180
Uniprot
Q86U86
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Sekine, I., et al., Oncogene. 2005 Apr 14;24(16):2735-8. 2. Shibata, Y., et al., Dev Biol. 2012 Jan 15;361(2):349-57.