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Home / Proteins & Peptide

p38alpha, GST-tag

SKU : BHP18200153

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BPS Bioscience

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Mfr.No.	40070
Description	Recombinant full-length human p38alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_139012. host species: Sf9 cells Host species: Sf9 cells Specific activity: 77 pmol/min/ug
Background	p38alpha (SAPK2A) is a member of the p38 MAPK family which are activated by various environmental stresses and proinflammatory cytokines (1). The activation of p38 requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase (2). The substrates of p38 include transcription regulator ATF2, MEF2C, MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Immunogen Region	1-360(end)
Tag	N-terminal GST-tag
Formulation	50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_139012
Mw(kda)	67 kDa

Synonyms	CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, MAPK14
Uniprot	Q16539

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Purity	>=90%
Storage	At least 6 months at -80°C.

Reference	1. Han, J. et al., Science 265: 808-811, 1994. 2. Ge, B. et al., Science 295: 1291-1294, 2002.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200153	40070	10 ug	$418		Add to Cart

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