Human secreted OX40, Fc fusion protein,also known as Tumor Necrosis FactorReceptor Superfamily Member 4,TNFRSF4, and CD134, GenBankAccession No. NM_003327, a.a. 29-216expressed in a HEK293 cell expressionsystem. MW = 46.8 kDa (monomer). Thisprotein runs at a higher MW by SDS-PAGEdue to glycosylation.
Immunogen Region
29-216
Tag
C-terminal Fc fusion (Human IgG1)
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Endotoxin Level
<1 EU/ug
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_003327
Mw(kda)
46.8 kDa
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, CD134
Uniprot
P43489
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution.
Storage
At least 6 months at -80°C.
Reference
1. Rogers, P.R. et al., Immunity. 2001; 15(3): 445-455. 2. Ito, T. et al., J. Exp. Med. 2005; 202(9): 1213-1223.