Human secreted OX40, also known asCD134, Tumor Necrosis Factor ReceptorSuperfamily Member 4, and TNFRSF4,GenBank Accession No. NM_003327, a.a.29-216 with C-terminal Avitag and Histag,expressed in a HEK293 cell expressionsystem. This protein is enzymatically biotinlabeledusing Avitag technology. MW =23.6 kDa (monomer). This protein runs at ahigher MW by SDS-PAGE due toglycosylation. Biotinylation was confirmed tobe>90%.
Immunogen Region
29-216
Tag
C-terminal Avitag and His-tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Species
Human
Application
Useful for studying protein binding, screening small molecules, and in vitro cellular assays.
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_003327
Mw(kda)
23.6 kDa+glycans
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, CD134
Uniprot
P43489
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Rogers, P.R. et al., Immunity. 2001; 15(3): 445-455. 2. Ito, T. et al., J. Exp. Med. 2005; 202(9): 1213-1223.