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Home / Proteins & Peptide

NLRP3 (delPYD) / NEK7 Complex

SKU : BHP18200965

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Mfr.No.	100477
Description	NLRP3 (delPYD)/NEK7 complex of human NLRP3 also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1 (GenBank Accession No. NM_004895), a.a. 134-1036(end) with N-terminal FLAG-tag, MW=105 kDa, and human NEK7 also known as NIMA (Never In Mitosis Gene A)-Related Kinase 7 (GenBank Accession No. NM_133494), a.a. 2-302(end) with N-terminal His-tag, MW= 37 kDa. Co-expressed in a HEK293 expression system.
Immunogen Region	NLRP3: 134-1036(end); NEK7: 2-302(end)
Tag	NLRP3: N-terminal FLAG-tag; NEK7: N-terminal His-tag
Formulation	20 mM Tris-HCl, pH 7.5, 200 mM NaCl, 0.5 mM TCEP and 10% glycerol.
Species	Human
Notes	Avoid freeze/thaw cycles.
GenBank	NLRP3: NM_004895; NEK7: NM_133494
Mw(kda)	NLRP3: 105 kDa; NEK7: 37 kDa

Synonyms	NLRP3: NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin, PYPAF1 NEK7: NIMA (Never In Mitosis Gene A)-Related Kinase 7
Uniprot	NLRP3: Q96P20; NEK7: Q8TDX7

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. He, Y., et al. Nature, 2016 Feb; 530: 354-357. 2. He, Y., et al. Trends in Biochem. Sci. 2016 Dec; 41(12):1012-1021.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200965	100477	10 ug	$621.50		Add to Cart

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