Human NKp46, also known as CD335, Natural Cytotoxicity Triggering Receptor 1, Lymphocyte Antigen 94 Homolog, and Natural Killer Cell P46-Related Protein, GenBank Accession No. NM_004829, a.a. 22-258, fused at the C-terminus with the Fc portion of human IgG1 followed by a C-terminal Avi-tag and expressed in a HEK293 cell expression system. MW=56 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation. This protein is enzymatically biotinylated using Avi-Tag technology. Biotinylation is confirmed to be>=90%.
Immunogen Region
22-258
Tag
C-terminal Fc-Avi-Tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Human
Notes
Avoid freeze/thaw cycles.
GenBank
NM_004829
Mw(kda)
56 kDa
Synonyms
CD335, Natural Cytotoxicity Triggering Receptor 1, Lymphocyte Antigen 94 Homolog, and Natural Killer Cell P46-Related Protein
Uniprot
O76036
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
Stable for at least 6 months at -80°C
Reference
1. Mandelboim, O., et al., Nature. 2001 Feb; 409: 1055-1060. 2. Mandelboim, O., et al., The Int’l J. of Biochem. & Cell Bio. 2001 Jul; 33(12): 1147-1150