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Home / Proteins & Peptide

NcoR2 (SMRT), GST-tag

SKU : BHP18200317

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Mfr.No.	50020
Description	Human NCOR2/SMRT, DAD domain, a.a. 395-489, GenBank Accession No. NM_006312, N-terminal GST-tag, MW= 39 kDa, expressed in E. coli system. Source: E. coli. Purity:> 60% by SDS-PAGE.
Background	NcoR2 , nuclear receptor corepressor, are transcriptional corepressors that play an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain , DAD, of NCOR2/SMRT is required for activation of the otherwise inert deacetylase.
Immunogen Region	395-489
Tag	N-terminal GST-tag
Formulation	50 mM Tris-HCl, pH 8.0, 138 mM NaCl, 20 mM glutathione, and 10%glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_006312
Mw(kda)	39 kDa

Synonyms	nuclear receptor corepressor 2, Silencing mediator of retinoic acid and thyroid hormone receptor, TRAC-1, SMRT, NcoR2
Uniprot	Q9Y618

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	Codina, A. et al., Proc. Natl. Acad. Sci. USA, 102, 6009-6014, (2005)

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200317	50020	50 ug	$462		Add to Cart

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