Mouse secreted Programmed Cell Death 1(PD-1)-Fc fusion protein, also known asCD279, PDCD1, and SLEB2, GenBankAccession No. NM_008798, a.a. 25-167,fused at the C-terminus to the Fc portion ofmouse IgG2a, expressed in a HEK293 cellexpression system. MW = 43.2 kDa. Note:this protein runs at an apparent highermolecular weight due to glycosylation.
Immunogen Region
25-167
Tag
C-terminal Fc fusion (Mouse IgG2a)
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Species
Mouse
Application
Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_008798
Mw(kda)
43.2 kDa
Synonyms
Programmed Cell Death 1, CD279, PDCD1, SLEB2
Uniprot
Q02242
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution.
Storage
At least 6 months at -80°C.
Reference
1. Agata, Y., et al., Int. Immunol. 1996; 8(5): 765-772. 2. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7): 1027-1034.