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Home / Proteins & Peptide

Mouse Fas / Tumor necrosis factor receptor superfamily member 6 Recombinant Protein

SKU : BHP13800320

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R0030m
Alternative Names	Apo-1 antigen,Apoptosis-mediating surface antigen FAS,FASLG receptor,CD95,Apt1,Tnfrsf6
Source	E.coli
Species	Mus Musculus (Mouse)
Accession Number	P25446
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Tumor necrosis factor receptor superfamily member 6
Entry Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Mw(kda)	16.28

Subunit	Binds DAXX (PubMed:9215629). Interacts with HIPK3 (PubMed:11034606). Part of a complex containing HIPK3 and FADD (By similarity). Binds RIPK1 and FAIM2. Interacts with BRE and FEM1B. Interacts with FADD (By similarity). Interacts directly (via DED domain) with NOL3 (via CARD domain); inhibits death-inducing signaling complex (DISC) assembly by inhibiting the increase in FAS-FADD binding induced by FAS activation (PubMed:15383280). Interacts with CALM.
Gene Name	Fas
Sequence	22-169aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800320	R0030m	50µg	$637.78		Add to Cart
BHP13800320	R0030m	100µg	$904.44		Add to Cart
BHP13800320	R0030m	200µg	$1348.89		Add to Cart
BHP13800320	R0030m	0.5mg	$1971.11		Add to Cart
BHP13800320	R0030m	1mg	$2682.22		Add to Cart
BHP13800320	R0030m	5mg	$4637.78		Add to Cart
BHP13800320	R0030m	10mg	$6148.89		Add to Cart

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