Mouse secreted CD137, also known as Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA, GenBank Accession No. NM_001561, a.a. 24-187, fused at the Cterminus to the Fc portion of mouse IgG2a, with a C-terminal AviTag expressed in a HEK293 cell expression system. MW = 46.7 kDa (monomer). This protein runs at a higher MW by SDSPAGE due to glycosylation.
Immunogen Region
24-187
Tag
C-terminal Fc fusion (mIgG2a), AviTag
Formulation
8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Species
Mouse
Application
Useful for studying protein binding and screening small molecular inhibitors
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_001561
Mw(kda)
46.7 kDa (monomer)
Synonyms
Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, ILA, 4-1BB
Uniprot
P20334
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659. 2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.